Developing a Personalized Vaccine Against Cancerous Brain Tumors | Technology Networks

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Investigators at theĀ UCLA Health Jonsson Comprehensive Cancer CenterĀ have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.

The study, published inĀ Nature Communications, found that pairing a personalized dendritic cell vaccine with the immune-boosting substance poly-ICLC enhances the immune response and activity of T cells in patients with malignant glioma, and improves the dendritic cellsā€™ ability to fight the brain tumor more effectively than the vaccine alone.

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